MYC

MYC plays a crucial role in both the beginning and continuation of cancer development. ...Numerous types of cancers rely on continuous activation of MYC. Tumorigenesis is initiated by MYC through escaping various mechanisms that suppress tumor growth. A well-known fundamental function of MYC is induction of apoptosis. MYC transcription factor has a dual role in tumor cells. It can activate and repress various downstream pathways that can induce proliferation or apoptosis. Myc amplification is detected in numerous types of cancer such as breast, colorectal, pancreatic, gastric, and uterine cancers.