Ganzyme B

Granzyme B is a highly cytotoxic agent that natural killer cells and cytotoxic T ...lymphocytes utilize to destroy specific malignant or diseased cells. An increasing amount of information indicates that there additional functions outside cell death, such as tissue growth and repair. GZMB is a prospective prognostic marker for colorectal cancer and is linked to the advancement of liver cancer. Moreover, GZMB expression variations over time in non-small-cell lung cancer could be used as a biomarker to track the effectiveness of immune checkpoint inhibitor monotherapy.