CD47

CD47 has a significant impact on controlling the tumor microenvironment and avoiding detection by ...the immune system, which makes it an appealing target for cancer therapy. The inhibition of CD47 not only increases the ability of macrophages to engulf cancer cells, but it also directly affects the functioning of stromal cells and the tumor microenvironment (TME). CD47 expression present in head and neck cancer, kidney cancer, myeloma, ovarian cancer, pancreatic cancer, and sarcoma.