CD3

CD3 is a marker that can be used to identify all types of T-cells ...present in the peripheral blood and lymphoid tissues, including thymocytes and mature T-cells. The CD3 complex is responsible for detecting the initial signal that activates the TCR of the lymphocyte. As a result, it becomes a highly appealing receptor for determining the outcome of the immune response in various situations, ranging from inducing tolerance to activating the immune system. The CD3 protein complex plays a crucial role in identifying and categorizing T-cell cancers such as malignant lymphomas and leukemias.