CD11B

CD11b plays a significant role in numerous monocytic/macrophage reactions during the immune ...inflammatory response, and it is closely linked to the macrophages’ ability to engulf and digest foreign particles. CD11b controls the polarization of macrophages by regulating the transcription of proinflammatory macrophage genes. This prevents the development of immunosuppressive macrophages and enhances the anti-tumor immune responses in both mouse and human tumor models. As a result, this improvement in immune response leads to increased
survival rates.CD11b is present on breast cells.