CCR2

CCR2 can also be found in various types of cells, including tumor cells. The ...communication pathway of CCR2 in monocytes/macrophages and T cells plays a significant role in cancer immunity. Additionally, growing evidence suggests that cancer cells can use CCR2 to enhance their own survival, growth, and ability to spread to other parts of the body. The increased expression of CCR2 and varied immune conditions in prostate cancer is linked to the progression, spread, and recurrence of the disease. The overexpression of CCR2 and its subsequent stimulation of tumor development have also been detected in various types of cancers, including breast, ovarian, esophageal, gastric, renal cell, lung, colon, and papillary thyroid cancers.