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Deciphering Molecular Symphony of Spatial Biology by Omicsveu

Multiomics isn’t just about individual cellular systems or components—it’s about decoding life’s symphony. As we continue this journey, precision medicine awaits—a personalized concerto for each patient. So, let’s listen closely, analyze passionately, and compose a healthier future.

Introduction

Biological mechanism can be described as a molecular symphony where each molecule, be it nucleic acid or protein, plays a crucial role. Singularly, these components do not convey the gist of the symphony, but when combined and execute under the careful instruction of a conductor, the grand symphony is revealed. Thus, understanding the molecular composition, interactions, and functions is essential for unraveling the mysteries of health, disease, and personalized medicine. This is the era of multiomics.

What Are Multiomics?

Multi-omics is the combination of different “omics” Here are some key players in the omics ensemble:

1. Genomics: The study of an organism’s complete set of DNA (its genome). Genomics helps us understand genetic variations, hereditary diseases, and evolutionary relationships.

2. Epigenomics: Epigenetic modifications (such as DNA methylation) influence gene expression without altering the underlying DNA sequence. Epigenomics explores these subtle notes that shape our health.

3. Transcriptomics: Focusing on RNA, transcriptomics reveals which genes are active (expressed) in a given tissue or under specific conditions. It’s like listening to the orchestra tuning up before the concert.

4. Proteomics: Proteins are the workhorses of the cell. Proteomics investigates their abundance, modifications, and interactions. Imagine each protein as a musician playing a unique instrument.

5. Metabolomics: Metabolites are small molecules involved in cellular processes. Metabolomics captures the dynamic dance of these molecules—think of it as the rhythm section of the orchestra.

Individual Parts of The Symphony:

Advancements in sequencing, labeling, and automation have revolutionized the field of multiomics. We can now examine spatially, the presence or absence of individual omics components at the cellular and tissue level. But this information isn’t a harmonious melody which conveys the story of the symphony.

Introducing Omicsveu

Omicsveu steps onto the stage as fully automated multiplex multiomics solution. With the automated slide staining system, ready-to-use probes, antibodies, kits, and reagents, the entire suite of multiomics spatial biology technologies work together to harmonize the multiomics analysis and visualization. Here’s what makes it stand out:

NanoVIP: The NanoVIP® system offers a broad range of spatial multiplex multi-omics solutions consisting of a fully automated staining system, ready-to-use probes, multiplexing antibodies, visualization kits and consumables for spatial biology. The system includes the EZ-AR Elegance Line for an all-in-one de-wax rehydration and universal retrieval solution for all proteins and nucleic acids. NanoVIP® is an all-in-one fully automated system, from microtome to slides, ready for imaging and imaging mass cytometry.

State-of-the-art Automation:

Micro-chamberreduces total reaction volumes

Precision pipetting- dispenses and maintains accurate volume

Independent workstations- customizable individual protocols for each workstation

24 Reagent vials- minimizes dead volume with 1.5mL inserts

Precision temperature- Peltier technology ensures accurate temperature maintenance on each slide position

Eco-friendly- complete xylene-free system generates low-volume waste from washes

 

Spatial Biology Technologies: Omicsveu offers a complete suite of technologies which include:

PhenoveuProteomics profiling
Phenoveu is a multiplexing immunofluorescence (IF) technique that allows simultaneous localization of multiple biomarkers

RNAveu—Multiplex mRNA transcripts
Spatial transcriptomics is a powerful means to visualize the expression patterns of multiple nucleic acid targets in an individual cell in the spatial context.

Transcriptomics & PhenomicsTranscription and translation in  one
The co-localization of proteins, mRNA, DNA, and miRNA in the same tissue sections to provide valuable insights into cellular processes.

miRNAveu—Multiplexing miRNAs
Our miRNA probes portfolio offers over 220 unique miRNA probes designed specifically for identifying cancer of unknown primary, staging and grading cancers, and characterization of poorly differentiated tumors.

In situ SequencingIdentify the presence and spatial location of point mutations
ISS enables the detection and spatial mapping of nucleic acid sequences within the tissue, allowing researchers a unique perspective on gene expression within spatial context.

RNAveu and Phenoveu

Conclusion

Multiomics isn’t just about individual cellular systems or components—it’s about decoding life’s symphony. As we continue this journey, precision medicine awaits—a personalized concerto for each patient. So, let’s listen closely, analyze passionately, and compose a healthier future.

 

For more information, visit the Spatial Multiomics page and explore the Multiomics technologies by Omicsveu.

Contact us for more information on Multiomics: https://omicsveu.com/contact/

 

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