FREMONT, CALIFORNIA, USA, January 3, 2024
Omicsveu driven to harness and accelerate multiplex multi-omics Spatial Biology research, proudly announces unveiling of an advanced technology – RNAveu that enables multiplexing of up to 40 RNA transcripts with single-gene sensitivity, and only two hybridization steps. Further, system is designed to colocalize DNA, RNA, mRNA, miRNA, and protein biomarkers.
RNAveu is a cutting-edge multiplexing technology that allows in situ localization of tumor-specific biomarkers to diagnose tumor heterogeneity and elucidate tumor microenvironment to improve characterization of tumor for better diagnostic and therapeutic modalities. Unlike traditional techniques that primarily focus on protein expression, RNAveu is designed to visualize a single copy gene with only two hybridization steps. Cocktail of multiple transcript-specific probes with DNA barcode on both 3’ and 5’ ends hybridize to specific sequences on target gene followed by hybridization of visualization probe on both ends with complimentary barcode sequences which are conjugated with 20 fluorophores. The RNAveu protocol provides reproducible, robust assay for distinct clean, intense signal for localization of single copy gene.
“RNAveu is a trailblazer in the realm of spatial transcriptomics, a field dedicated to understanding RNA expression in their native context within tissues. Its ability to uncover the cellular profiling of mRNA within cells is transforming our understanding of tumor biology, development, and diseases” said Dr. Krishan Kalra, CEO of Omicsveu.
Download RNAveu Brochure: http://bit.ly/RNAveu_Brochure
Trending Blog on RNAveu: https://bit.ly/RNAveu_Blog
Know more about RNAveu: https://omicsveu.com/rnaveu-products
We deliver the most innovative and powerful biomedical tools that fuel Spatial Biology discoveries to meet other life science challenges of today. Our fully automated and integrated systems are affordable, simple, fast to accelerate precision oncology research, reduce cost, improve disease outcome, and enhance patient quality of life.
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Omicsveu, a multiplex multiomics spatial biology company, proudly announces unveiling of an advanced spatial biology system. This innovative technology promises to accelerate Spatial Multiplex Multiomics research.
The cornerstone of Omicsveu’s breakthrough lies in its spatial biology multiplex multiomics system, integrated state-of-the-art fully automated staining system- NanoVIP® encompassing five innovative technologies. This high-precision sophisticated system allows for the simultaneous localization of high-resolution genomics, transcriptomics, and proteomics. Multifaceted technologies play a pivotal role in scrutinizing the diverse cellular compositions and biomarkers within tumor microenvironment.
“Comprehensive characterization of the cellular and molecular architecture within tumor microenvironments yields valuable insights. This meticulous analysis enables the identification of novel cancer-associated genomic and proteomic biomarkers, significantly accelerating the discovery and development of cutting-edge diagnostic and therapeutic modalities.” said Dr. Krishan Kalra, CEO of Omicsveu.
Omicsveu offers a set of tools that include fully automated spatial multi-omics slide staining protocols:
• RNAveu – detection of mRNA by using uniquely labeled fluorophore-tagged barcoded probes.
• Phenoveu – multiplexed immunofluorescence technique that simultaneously detects multiple biomarkers in a single section of FFPE tissue.
• miRNAveu spatial location of miRNA sequences.
• Genotyping and Phenotyping – co-localization of proteins, mRNA and miRNA
• In situ sequencing– to identify the presence and spatial location of mRNA sequences
These five multi-omics tools offer extensive multiplexing capabilities, featuring a fully automated All-in-One NanoVIP® instrument.
Download NanoVIP Technologies Brochure: https://bit.ly/NanoVIP_Technologies
Fully automated NanoVIP® protocols have been developed for commercially available spatial biology assays like Hyperion™, Opal™, and RNAscope™ which don’t require highly skilled manpower or long training cycle with the following additional benefits:
• Reduced hands-on time
• Reduced reagent cost
• Reduced total assay time
Download NanoVIP Application Brochure: https://bit.ly/NanoVIP_Applications
To know more about NanoVIP, visit https://omicsveu.com/product/nanovip/